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The studys strengths embody its use of a giant population-based case-management design with careful ascertainment and classifcation of congenital coronary heart defects, adjustment for a number of potential confounders, and an skilled-based assessment of potential pesticide exposure. Rebecka Hjort, thanks for being such a nice and kind individual, for all the good talks, and on your invaluable assist with my Swedish citizenship. Adjusting the model for extremely correlated variables can introduce a big bias in a non�predictable direc� tion. Specifically, proof for liver tumors in rats includes a small number of hepatocellular carcinomas noticed in feminine rats at 50 and 250 mg/kg-day, which reached statistical significance (for development and for individual pairwise comparisons) solely with the combined grouping of neoplastic nodules and hepatocellular carcinomas. 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